XBI · WMTMT

May 28Jun 22Jul 15Aug 5Aug 27

Breadth

116 / 147

stocks rose with the index

Concentration

20%

of the gain from MRNA, TWST, APGE

Biggest driver

MRNA +3.43

MODERNA INC, +200.13%

Biggest drag

CAPR −0.62

CAPRICOR THERAPEUTICS INC, −65.44%

What drove it

147 members · drivers first · 3M · residual 106.2bp exceeds 60bp gate

The XBI rose 23.71% (+32.25 pts) over the past three months in a broad advance: 116 of 147 stocks rose, with MRNA out front at +3.43 points.

Read the latest market-close note: Salesforce and Nvidia Carry Their Indexes While Most Stocks Fall Behind

+36.4 pts from 119 gainers−4.3 pts from 28 losers

net +32.3 pts · gainers outweigh losers 8.4 to 1

Stock

Points

Return

XBIsum of all 147 stocks

+32.3

+23.71%

MRNAMODERNA INC

+3.4

+200.13%

TWSTTWIST BIOSCIENCE CORP

+1.9

+121.79%

APGEAPOGEE THERAPEUTICS INC

+1.0

+73.43%

NTRANATERA INC

+0.9

+58.32%

HALOHALOZYME THERAPEUTICS INC

+0.9

+56.82%

ORKAORUKA THERAPEUTICS INC

+0.9

+66.51%

QUREUNIQURE NV

+0.8

+99.44%

IOVAIOVANCE BIOTHERAPEUTICS INC

+0.8

+92.09%

KYMRKYMERA THERAPEUTICS INC

+0.8

+47.59%

ERASERASCA INC

+0.8

+59.75%

PTGXPROTAGONIST THERAPEUTICS INC

+0.7

+48.89%

TVTXTRAVERE THERAPEUTICS INC

+0.7

+41.37%

RVMDREVOLUTION MEDICINES INC

+0.7

+43.02%

TGTXTG THERAPEUTICS INC

+0.6

+43.53%

RLAYRELAY THERAPEUTICS INC

+0.6

+39.71%

117 othersclick to expand the full index

+20.5

SPRYARS PHARMACEUTICALS INC

−0.1

−35.85%

UTHRUNITED THERAPEUTICS CORP

−0.1

−6.08%

VERAVERA THERAPEUTICS INC

−0.1

−3.51%

TYRATYRA BIOSCIENCES INC

−0.1

−20.04%

MLYSMINERALYS THERAPEUTICS INC

−0.2

−17.53%

MPLTMAPLIGHT THERAPEUTICS INC

−0.2

−57.89%

NVAXNOVAVAX INC

−0.2

−12.31%

GLUEMONTE ROSA THERAPEUTICS INC

−0.2

−26.15%

ARDXARDELYX INC

−0.2

−38.88%

IONSIONIS PHARMACEUTICALS INC

−0.3

−19.27%

ALNYALNYLAM PHARMACEUTICALS INC

−0.3

−22.45%

SMMTSUMMIT THERAPEUTICS INC

−0.3

−17.69%

SIONSIONNA THERAPEUTICS INC

−0.3

−85.84%

CELCCELCUITY INC

−0.6

−28.78%

CAPRCAPRICOR THERAPEUTICS INC

−0.6

−65.44%

Cap weighting, illustrated

ARROWHEAD PHARMACEUTICALS IN and OVID THERAPEUTICS INC moved almost identically (+12.07% vs +10.98%), yet ARWR moved the XBI 30.9× as much. In a cap-weighted index, the bigger company's weight turns the same percentage move into far more points.

Attribution map

slicing the +32.25 pt move · cell size = points contributed · color = direction, intensity = return

MRNA+3.4 pts(+200.1%)

TWST+1.9 pts(+121.8%)

APGE+1.0 pts

NTRA+0.9 pts

HALO

ORKA+0.9 pts(+66.5%)

QURE+0.8 pts(+99.4%)

IOVA+0.8 pts

KYMR+0.8 pts

ERAS+0.8 pts

PTGX

TVTX+0.7 pts(+41.4%)

RVMD+0.7 pts(+43.0%)

CAPR−0.6 pts

CELC−0.6 pts

TGTX

RLAY

SLS+0.5 pts

CDNA+0.5 pts

SYRE

REGN

ACAD+0.5 pts

XNCR+0.5 pts

CGON

DYN

IDYA+0.4 pts

TRAX+0.4 pts

AMGN

REPL

IMVT

SRRK

VRDN

PURR

DNTH+0.4 pts

SION−0.3 pts

BHVN

ALKS+0.3 pts

IMNM

ARWR+0.3 pts

SMMT−0.3 pts

PGEN

ALNY

KRYS

ZBIO

DNLI

IONS

CLDX

VKTX

CRSP

ABSI

SRPT

ADMA

GLUE

RCUS

VOR

IRON

NVAX

ARQT

PVLA

CADL

AVTX

RARE

VCEL

MPLT

BCRX

27 more

MLYS

KURA

GILD

Concentration curve

cumulative share of the +32.25 pt move · sorted by contribution

When they drove it

cumulative points through the period

Breadth

member returns, this period

−100%0%+100%+200%

From −85.84% (SION) to +233.33% (REPL). Equal-weight, the XBI would be +25.76% vs the actual +23.71%; the gap is what cap weighting did.

By sector

point contribution · sums to +32.25 pts

-147

+32.1

The year, session by session

every trading day of 2026 · hover for the move

JANFEBMARAPRMAYJUNJULAUG

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SPDR S&P Biotech ETF

What drove it

Attribution map

Concentration curve

When they drove it

Breadth

By sector

The year, session by session

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