XBI · WMTMT

open11:0512:4514:2016:00

5-minute bars · index reconstructed live from member prices

Breadth

128 / 154

stocks rose with the index

Concentration

20%

of the gain from MRNA, IOVA, PCVX

Biggest driver

MRNA +0.45

MODERNA INC, +14.21%

Biggest drag

PRAX −0.03

PRAXIS PRECISION MEDICINES I, −1.40%

Context

94th pctile

of the past year's sessions by daily move

What drove it

154 members · drivers first · 1D · residual 14.2bp within 60bp gate

The XBI rose 2.99% (+4.46 pts) on the day in a broad advance: 128 of 154 stocks rose, with MRNA out front at +0.45 points.

Read the latest market-close note: Goldman and Microsoft Push the Dow to a Large Gain While Telecoms Sink Communication Services

+4.6 pts from 128 gainers−0.2 pts from 24 losers

net +4.5 pts · gainers outweigh losers 27.9 to 1

Stock

Points

Return

XBIsum of all 154 stocks

+4.5

+2.99%

MRNAMODERNA INC

+0.5

+14.21%

IOVAIOVANCE BIOTHERAPEUTICS INC

+0.2

+9.84%

PCVXVAXCYTE INC

+0.2

+9.79%

SYRESPYRE THERAPEUTICS INC

+0.2

+7.25%

TWSTTWIST BIOSCIENCE CORP

+0.1

+5.08%

CRSPCRISPR THERAPEUTICS AG

+0.1

+5.85%

GRALGRAIL INC

+0.1

+6.01%

ORKAORUKA THERAPEUTICS INC

+0.1

+6.25%

NVAXNOVAVAX INC

+0.1

+15.80%

KODKODIAK SCIENCES INC

+0.1

+5.95%

IBRXIMMUNITYBIO INC

+0.1

+6.05%

RXRXRECURSION PHARMACEUTICALS A

+0.1

+10.38%

ARQTARCUTIS BIOTHERAPEUTICS INC

+0.1

+8.53%

MIRMMIRUM PHARMACEUTICALS INC

+0.1

+5.73%

ABSIABSCI CORP

+0.1

+13.65%

124 othersclick to expand the full index

+2.3

JANXJANUX THERAPEUTICS INC

−0.0

−0.59%

TRAXFIRST TRACKS BIOTHERAPEU W/I

−0.0

−0.50%

ANABANAPTYSBIO INC

−0.0

−0.56%

IRWDIRONWOOD PHARMACEUTICALS INC

−0.0

−1.29%

AGIOAGIOS PHARMACEUTICALS INC

−0.0

−0.34%

BMRNBIOMARIN PHARMACEUTICAL INC

−0.0

−0.17%

OCGNOCUGEN INC

−0.0

−2.24%

CAPRCAPRICOR THERAPEUTICS INC

−0.0

−2.25%

MNPRMONOPAR THERAPEUTICS INC

−0.0

−5.98%

SPRYARS PHARMACEUTICALS INC

−0.0

−7.24%

MNKDMANNKIND CORP

−0.0

−3.80%

SRPTSAREPTA THERAPEUTICS INC

−0.0

−1.98%

PURRHYPERLIQUID STRATEGIES

−0.0

−1.68%

MDGLMADRIGAL PHARMACEUTICALS INC

−0.0

−1.08%

PRAXPRAXIS PRECISION MEDICINES I

−0.0

−1.40%

Cap weighting, illustrated

MODERNA INC and KAILERA THERAPEUTICS INC moved almost identically (+14.21% vs +16.10%), yet MRNA moved the XBI 15.8× as much. In a cap-weighted index, the bigger company's weight turns the same percentage move into far more points.

Attribution map

slicing the +4.46 pt move · cell size = points contributed · color = direction, intensity = return

MRNA+0.5 pts(+14.2%)

IOVA+0.2 pts

PCVX+0.2 pts(+9.8%)

SYRE+0.2 pts

TWST+0.1 pts

CRSP+0.1 pts

GRAL

ORKA+0.1 pts(+6.3%)

NVAX+0.1 pts(+15.8%)

KOD+0.1 pts(+6.0%)

IBRX+0.1 pts(+6.1%)

RXRX+0.1 pts(+10.4%)

ARQT+0.1 pts(+8.5%)

MIRM+0.1 pts

ABSI+0.1 pts

TGTX+0.1 pts

IONS+0.1 pts(+4.6%)

BIIB+0.1 pts(+3.3%)

TNGX+0.1 pts

UTHR+0.1 pts

ERAS+0.1 pts

ALNY+0.1 pts

NTRA+0.1 pts

ROIV+0.1 pts

GILD+0.1 pts

PTGX

VCYT

BEAM

COGT+0.1 pts

ARWR+0.1 pts

AMGN

VKTX

PVLA

DNLI

RLAY

SLS

EXEL

NTLA

VRTX

CDNA

KRYS

CYTK

BCRX

PRAX

SMMT

MDGL

VIR

MLYS

REGN

PGEN

PURR

SRPT

ZBIO

Concentration curve

cumulative share of the +4.46 pt move · sorted by contribution

When they drove it

cumulative points through the period

Breadth

member returns, this period

−10%−5%0%+5%+10%+15%

From −7.24% (SPRY) to +16.10% (KLRA). Equal-weight, the XBI would be +2.31% vs the actual +2.99%; the gap is what cap weighting did.

By sector

point contribution · sums to +4.46 pts

-154

+4.5

The year, session by session

every trading day of 2026 · hover for the move

JANFEBMARAPRMAYJUNJULAUGSEPOCT

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SPDR S&P Biotech ETF

What drove it

Attribution map

Concentration curve

When they drove it

Breadth

By sector

The year, session by session

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