XBI · WMTMT

open10:1011:0011:4512:30

5-minute bars · index reconstructed live from member prices

Breadth

104 / 147

stocks fell with the index

Concentration

56%

of the decline from MRNA, SYRE, RLAY

Biggest driver

MRNA −0.34

MODERNA INC, −7.27%

Biggest offset

ERAS +0.17

ERASCA INC, +8.42%

Context

26th pctile

of the past year's sessions by daily move, so far

What drove it

147 members · detractors first · 1D · reconstructed from each member's latest trade price; official close pending

The XBI is down 0.77% (−1.30 pts) so far today, and 56% of that decline came from just three stocks: MRNA, SYRE, RLAY.

Read the latest market-close note: Nvidia and Goldman Sachs Lead a Narrow Advance as Energy and Staples Slide

+1.0 pts from 43 gainers−2.3 pts from 103 losers

net −1.3 pts · losers outweigh gainers 2.3 to 1

Stock

Points

Return

XBIsum of all 147 stocks

−1.3

−0.77%

MRNAMODERNA INC

−0.3

−7.27%

SYRESPYRE THERAPEUTICS INC

−0.3

−13.29%

RLAYRELAY THERAPEUTICS INC

−0.1

−5.40%

GRALGRAIL INC

−0.1

−3.96%

ACADACADIA PHARMACEUTICALS INC

−0.1

−3.43%

SLSSELLAS LIFE SCIENCES GROUP I

−0.1

−3.26%

CRSPCRISPR THERAPEUTICS AG

−0.1

−3.24%

IOVAIOVANCE BIOTHERAPEUTICS INC

−0.1

−3.14%

BEAMBEAM THERAPEUTICS INC

−0.0

−3.22%

PURRHYPERLIQUID STRATEGIES

−0.0

−4.00%

ABSIABSCI CORP

−0.0

−5.86%

NTLAINTELLIA THERAPEUTICS INC

−0.0

−3.40%

KYMRKYMERA THERAPEUTICS INC

−0.0

−1.46%

CLDXCELLDEX THERAPEUTICS INC

−0.0

−2.60%

TVTXTRAVERE THERAPEUTICS INC

−0.0

−1.33%

117 othersclick to expand the full index

−0.8

INBXINHIBRX BIOSCIENCES INC

+0.0

+2.36%

AVTXAVALO THERAPEUTICS INC

+0.0

+2.63%

IBRXIMMUNITYBIO INC

+0.0

+1.10%

CAPRCAPRICOR THERAPEUTICS INC

+0.0

+9.69%

PVLAPALVELLA THERAPEUTICS INC

+0.0

+2.61%

PGENPRECIGEN INC

+0.0

+3.30%

CELCCELCUITY INC

+0.0

+2.27%

VERAVERA THERAPEUTICS INC

+0.0

+3.03%

MDGLMADRIGAL PHARMACEUTICALS INC

+0.0

+2.62%

PRAXPRAXIS PRECISION MEDICINES I

+0.1

+2.31%

TNGXTANGO THERAPEUTICS INC

+0.1

+7.39%

SRRKSCHOLAR ROCK HOLDING CORP

+0.1

+4.11%

SMMTSUMMIT THERAPEUTICS INC

+0.1

+7.07%

BHVNBIOHAVEN LTD

+0.1

+13.29%

ERASERASCA INC

+0.2

+8.42%

Cap weighting, illustrated

RELAY THERAPEUTICS INC and MAPLIGHT THERAPEUTICS INC moved almost identically (−5.40% vs −4.63%), yet RLAY moved the XBI 10.4× as much. In a cap-weighted index, the bigger company's weight turns the same percentage move into far more points.

Attribution map

slicing the −1.30 pt move · cell size = points contributed · color = direction, intensity = return

MRNA−0.3 pts(−7.3%)

SYRE−0.3 pts(−13.3%)

ERAS+0.2 pts(+8.4%)

BHVN+0.1 pts

RLAY−0.1 pts

SMMT+0.1 pts(+7.1%)

SRRK+0.1 pts(+4.1%)

TNGX+0.1 pts(+7.4%)

GRAL−0.1 pts

ACAD−0.1 pts

SLS

CRSP−0.1 pts(−3.2%)

IOVA−0.1 pts(−3.1%)

PRAX+0.1 pts

BEAM−0.0 pts

MDGL+0.0 pts

VERA

PURR−0.0 pts

ABSI

NTLA

CELC+0.0 pts

KYMR−0.0 pts

TVTX−0.0 pts

IDYA−0.0 pts

REGN

ABBV

SRPT

CDNA−0.0 pts

NVAX−0.0 pts

PVLA

RXRX

RYTM

DYN

CAPR

TSHA

MLYS

IMMX

QURE

INBX

PRME

VKTX

KOD

INCY

RARE

ANNX

INSM

ORKA

Concentration curve

cumulative share of the −1.30 pt move · sorted by contribution

When they drove it

cumulative points through the period

Breadth

member returns, this period

−15%−10%−5%0%+5%+10%

From −13.29% (SYRE) to +13.29% (BHVN). Equal-weight, the XBI would be −0.72% vs the actual −0.77%; the gap is what cap weighting did.

By sector

point contribution · sums to −1.30 pts

-147

−1.3

The year, session by session

every trading day of 2026 · hover for the move

JANFEBMARAPRMAYJUNJULAUG

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What drove it

Attribution map

Concentration curve

When they drove it

Breadth

By sector

The year, session by session

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